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我系田瑞軍課題組在《自然》發表文章 國際頂級學術期刊Nature報道了南方科技大學化學系副教授田瑞軍團隊與美國Salk研究所Tony Hunter院士團隊針對胰腺癌的功能蛋白質組學研究工作。
南科大化學系譚斌團隊《科學》發表研究成果 南方科技大學化學系教授譚斌團隊在國際頂尖學術期刊《科學》(Science)上以長文的形式在線發表了論文。解決了近60年來合成化學家一直挑戰的科學難題
2018年國家杰出青年科學基金獲得者譚斌教授 近日,國家自然科學基金委員會公布2018年度國家杰出青年科學基金評審結果,南方科技大學化學系譚斌教授獲得資助。
化學系張緒穆課題組在《美國化學會志》再次發表論文 近日,我?;瘜W系講座教授張緒穆課題組再次在國際頂尖化學期刊《美國化學會志》 (J. Am. Chem. Soc., IF = 14.357)上發表論文。
化學系何鳳課題組在《Joule》上發表重要研究成果 近日,我?;瘜W系副教授何鳳課題組在聚合物太陽電池領域取得重要研究進展,該成果發表在著名國際期刊Cell 旗下姐妹刊《Joule》
何鳳課題組在《自然通訊》上發表重要研究成果 近日,我?;瘜W系副教授何鳳課題組在聚合物二維超分子自組裝領域上取得重要研究進展,該成果發表在著名國際期刊《Nature Communications》(影響因子12.124)
徐晶課題組在《德國應用化學》發表VIP論文 該論文同時被該期刊選為VIP(Very Important Paper)與封底論文(Back Cover)。恰逢中國春節,該封底設計為中國傳統窗花形式,嵌入Astellatol分子三維結構、福字和南科大Logo,充滿節日喜慶氣氛。
南科大化學系本科生在《德國應用化學》發表論文 近日,我?;瘜W系本科生陳偉豪(第一作者,我校13級本科生,2017年畢業)及陳陽(我校15級本科生)在國際頂尖化學期刊《德國應用化學》(Angew. Chem. Int. Ed.)上發表論文。

李鵬飛

副教授

化學系

0755-88018319

lipf@sustech.edu.cn

研究方向
不對稱催化:有機催化;定向策略合成;化學生物學之識別催化

       李鵬飛,博士,副教授(研究員),深圳市海外高層次“孔雀計劃”人才(B類),深圳市南山區領航人才B類;中共南方科技大學委員會委員,化學系黨總支書記;深圳市南山區第五屆政協委員。于2009年中國科學院大連化學物理研究所獲有機化學博士學位,師從梁鑫淼研究員。2009-2011年先后在香港理工大學、香港浸會大學從事博士后研究工作,師從陳新滋院士。2012年起任南方科技大學化學系助理教授(副研究員),組建有機仿生催化課題組,獨立開展研究工作。2019年8月晉升為長聘副教授。該課題組致力于:1)不對稱催化研究領域,通過遠程立體控制實現立體中心的高效構建,具體體現在新型有機催化劑的研發及應用、高附加值化學品的策略合成;2)化學生物學:蛋白標記技術、磷酸化蛋白標準品的開發等研究方向。 


工作及教育背景

2019.08-           南方科技大學化學系,副教授(研究員) 

2012.01-2019.07 南方科技大學化學系,助理教授(副研究員)

2011.07-2011.12 香港浸會大學創意研究院,博士后研究員

  導師:陳新滋Albert S C Chan)院士

 2009.07-2011.07 香港理工大學應用生物及化學科技學系,助理研究員

  導師:陳新滋Albert S C Chan)院士

2006.09-2009.07 中國科學院大連化學物理研究所,有機化學 博士

  導師:梁鑫淼 研究員

2003.09-2006.07 大連理工大學化工學院,應用化學 碩士

  導師:李宗石 教授

1999.09-2003.07 青島大學化工學院,化學工程與工藝 學士

       15. 2019 南方科技大學“優秀黨務工作者”  

       14. 2018 南方科技大學“優秀員工” 

       13. 2018 南方科技大學“優秀工會干部”

       12. 2018 南方科技大學“優秀青年科研獎”

       11. 2018 南方科技大學“五年服務獎”

       10. 2018 南方科技大學“優秀共產黨員”

        9. 2017 南方科技大學 "優秀黨務工作者" 

        8. 2017 南方科技大學“招生工作先進個人”

        7. 2016 中共深圳市委教育工委系統“優秀黨務工作者”

        6. 2016 南方科技大學樹德書院“優秀導師”

        5. 2016 南方科技大學“優秀服務獎”

        4. 2016 深圳市南山區“領航人才B類”

        3. 2015 南方科技大學“招生工作先進個人”

        2. 2013 深圳市“孔雀計劃B類”

        1. 2012 南方科技大學“優秀員工”   

          

1)不對稱有機催化遠程控制高效構建立體中心

?    新型催化劑的設計、合成及其應用

?    高附加值化學品的策略合成 

2)化學生物學

?    蛋白標記技術

?    磷酸化蛋白標準品的開發

入職南方科技大學以來,主持的項目如下:

9. 2019 南方科技大學理學院教研序列教授“雙優”培育計劃 (Y01506003,10萬) 

8. 2019 廣東省功能分子工程重點實驗室開放基金項目 (2018kf01,2萬) 

7. 2018 國家自然科學基金委面上基金 (NSFC 21871128,65萬)

6. 2017 深圳市科創委基礎研究項目(JCYJ20170817110526264,30萬) 

5. 2016 深圳市科創委基礎研究項目(JCYJ20160429191918729,30萬) 

4. 2015 南方科技大學副校長基金 (FRG-SUSTC1501A-57,30萬)

3. 2013 國家自然科學基金委青年基金 (NSFC 21302089,25萬)

2. 2013 南方科技大學孔雀計劃啟動經費 (475+100萬)

1. 2012 南方科技大學基礎研究經費(68萬)  

Corresponding Author Journal Articles from SUSTech 


45. Lili Zhang,? Yuzhe Han,? Anqi Huang, Pei Zhang, Pengfei Li,* Wenjun Li.* Organocatalytic remote stereocontrolled 1,8-additions of thiazolones to propargylic aza-p-quinone methides (?co-first author). Org. Lett., 2019,

44. Chen Zhang,? Xinye Shang,? Yuyu Cheng,? Fushuai Li, Hanhui Zhao, Pengfei Li,* Wenjun Li.* Enantioselective construction of 3-substituted 3-amino-2-oxindoles containing an N,N-ketal skeleton via organocatalyzed aza-addition of isatin imines (?co-first author). Org. Biomol. Chem., 2019, 17, 8374–8378.

43. Yuyu Cheng, Zhiqiang Fang, Yanwen Jia, Zhongyue Lu, Wenjun Li,* Pengfei Li.* Organocatalytic enantioselective conjugate addition of 2-naphthols to ortho-hydroxyphenyl substituted para-quinone methides: access to unsymmetrical triarylmethanes. RSC Adv., 2019, 9, 24212–24217.

42. Yipeng Luan,? Anqi Huang,? Yuyu Cheng, Xiaohong Liu, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective Michael addition of oxazolones to 2-enoylpyridine N-oxides for assembling of pyridine N-oxides featuring vicinal oxygen-containing tetrasubstituted stereocenters (?co-first author). Adv. Synth. Catal., 2019, 361, 4208–4214.

41. Wei Lin, Xiao Lin, Yuyu Cheng, Xiaoyong Chang, San Zhou, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective direct vinylogous Michael addition of γ-substituted deconjugate butenolides to azadienes. Org. Chem. Front., 2019, 6, 2452–2456.

40. Pei Zhang,? Qiuhong Huang,? Yuyu Cheng, Rongshi Li,* Pengfei Li,* Wenjun Li.* Remote stereo-controlled construction of vicinal axially chiral tetrasubstituted allenes and heteroatom-functionalized quaternary carbon stereocenters (?co-first author). Org. Lett., 2019, 21, 503–507.

39. Pengfei Zhang, Xing Guo, Chang Liu, Wenjun Li,* Pengfei Li.* Enantioselective construction of pyridine N-oxides featuring 2,3-dihydrofuran motifs via phosphine catalyzed [4+1]-annulation of 2-enoylpyridine N-oxides with Morita-Baylis-Hillman carbonates. Org. Lett., 2019, 21, 152-155. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)

38. Chenxiao Qian,? Pangmiaomiao Zhang,? Wenjun Li,* Pengfei Li.* Phosphine catalyzed enantioselective [1 + 4]-annulation of Morita-Baylis-Hillman carbonates with α,β-unsaturated imines (?co-first author). Asian J. Org. Chem., 2019, 8, 242–245. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)

37. Wei Lin, Chen Zhang, Wen Xu, Yuyu Cheng, Pengfei Li,* Wenjun Li.* Organocatalytic asymmetric Michael addition of rhodanines to azadienes for assembling of sulfur-containing tetrasubstituted carbon stereocenters. Adv. Synth. Catal., 2019, 361, 476–480.

36. Tao Wang,? Pengfei Zhang,? Wenjun Li,* Pengfei Li.* Phosphine-mediated enantioselective [1+4]-annulation of Morita–Baylis–Hillman carbonates with 2-enoylpyridines (?co-first author). RSC Adv., 2018, 8, 41620–41623. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)

35. Kun Liu, Xinye Shang, Yuyu Cheng, Xiaoyong Chang, Pengfei Li,* Wenjun Li.* Regioselective [3+2]-annulation of hydrazonyl chlorides with 1,3-dicarbonyl compounds for assembling of polysubstituted pyrazoles. Org. Biomol. Chem., 2018, 16, 7811–7814.

34. Qiuhong Huang, Yuyu Cheng, Huijun Yuan, Xiaoyong Chang, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective Mannich-type addition of 5H-thiazol-4-ones to isatin-derived Imines: access to 3-substituted 3-amino-2-oxindoles featured by vicinal sulfur-containing tetrasubstituted stereocenters. Org. Chem. Front., 2018, 5, 3226–3230.

33. Fei Qi, Fang Fang, Pengfei Li.* Catalyst-free phospha-nucleophilic substitution of hydroxylactams by diarylphosphine oxide. Current Organocatalysis, 2018, 5, 145–149.

32. Bizhu Chu,? An He,? Yeteng Tian, Wan He, Peizhong Chen, Jintao Hu, Wenbin Zhou, Mingjie Zhang, Pengyuan Yang, Ying Sun,* Pengfei Li,* Tony Hunter, Ruijun Tian.* Photoaffinity engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples (?co-first author). Proc. Natl. Acad. Sci. USA, 2018, 115, E8863–E8872. (Highlighted by SUSTech News)

31. Yuyu Cheng, Zhiqiang Fang, Wenjun Li,* Pengfei Li.* Phosphine-mediated enantioselective [4+1] annulations between ortho-quinone methides and Morita-Baylis-Hillman carbonates. Org. Chem. Front., 2018, 5, 2728–2733. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)

30. Lili Zhang, Huijun Yuan, Wei Lin, Yuyu Cheng, Pengfei Li,* Wenjun Li.* Catalyst-controlled diastereodivergent construction of vicinal sulfur-functionalized quaternary and tertiary stereocenters. Org. Lett., 2018, 20, 4970–4974.

29. Qiuhong Huang, Lili Zhang, Yuyu Cheng, Pengfei Li,* Wenjun Li.* Enantioselective construction of vicinal sulfur-containing tetrasubstituted stereocenters via organocatalyzed Mannich-type addition of rhodanines to isatin imines. Adv. Synth. Catal., 2018, 360, 3266–3270.

28. Wenjun Li,* Xianhong Xu, Pengfei Zhang, Pengfei Li.* Recent advances in catalytic enantioselective reactions of para-quinone methides. Chem. Asian J., 2018, 13, 2350–2359. (Invited for the Special Issue on Homogeneous Catalysis from Young Investigators in Asia)

27. Wenjun Li,* Huijun Yuan, Zhantao Liu, Zhongyin Zhang, Yuyu Cheng, Pengfei Li.* NHC-catalyzed enantioselective [4 + 3] cycloaddition of ortho-hydroxyphenyl substituted para-quinone methides with isatin-derived enals. Adv. Synth. Catal., 2018, 360, 2460–2464. (說明: 說明: C:\Users\Lenovo\AppData\Local\Temp\1544704961(1).png Highly Cited Paper, Web of Science)

26. Wenjun Li,* Xianhong Xu, Yang Liu, Hua Gao, Yuyu Cheng, Pengfei Li.*  Enantioselective organocatalytic 1,6-addition of azlactones to para-quinone methides: an access to α,α-disubstituted and β,β-diaryl-α-amino acid esters. Org. Lett., 2018, 20, 1142–1145. (說明: 說明: C:\Users\Lenovo\AppData\Local\Temp\1544704961(1).png Highly Cited Paper, Web of Science)

25. Xinye Shang, Kun Liu, Zhongyin Zhang, Xianhong Xu, Pengfei Li,* Wenjun Li.* Direct access to spirobiisoxazoline via double 1,3-dipolar cycloaddition of nitrile oxide with allenoate. Org. Biomol. Chem., 2018, 16, 895–898.

24. Yuzhe Han, Yingzu Zhu, Pangmiaomiao Zhang, Wenjun Li,* Pengfei Li.* A catalyst-free cycloaddition reaction: access to spiro[chroman-3,2’-indene-1’,3’-dione] scaffolds. Chemistryselect, 2017, 2, 11380–11383.

23. Lili Zhang,? Xiao Zhou,? Pengfei Li, Zhantao Liu, Yang Liu, Yong Sun, Wenjun Li.* Asymmetric synthesis of chromene skeletons via organocatalytic domino reactions of in situ generated ortho-quinone methide with malononitrile and β-functionalized ketone (?co-first author). RSC Adv., 2017, 7, 39216–39220.

22. Yuyu Cheng,? Yuzhe Han,? Pengfei Li.* Organocatalytic enantioselective [1+4] annulation of Morita-Baylis-Hillman carbonates with electron-deficient olefins: access to chiral 2,3-dihydrofuran derivatives (?co-first author). Org. Lett. 2017, 19, 4774–4777. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)

21. Yuyu Cheng, Pengfei Zhang, Yanwen Jia, Zhiqiang Fang, Pengfei Li.* Organocatalytic condensation–ring opening–annulation cascade reactions between N-Bocindolin-2-ones/benzofuran-2(3H)-ones and salicylaldehydes for synthesis of 3-arylcoumarins. Org. Biomol. Chem., 2017, 15, 7505–7508. (Highlighted as Front Cover)

20. Lu Yu, Yuyu Cheng, Fei Qi, Rou Li, Pengfei Li.* Organocatalytic regioselective, diastereoselective, and enantioselective annulation of cyclic 1-azadiene with γ-nitro ketone via 3,4-cyclization. Org. Chem. Front., 2017, 4, 1336–1340.

19. Fei Qi, Rou Li, Fang Fang, Pengfei Li.* Autocatalytic nucleophilic substitution of hydroxylactam by thiophenol: access to N(acyl),S-acetals. Current Green Chemistry, 2016, 3, 235–241.

18. Jindian Duan, Yuyu Cheng, Jing Cheng, Rou Li, Pengfei Li.* Organocatalytic asymmetric benzylation and aldol-hemiacetalization of α,β-unsaturated trifluoromethyl ketones: efficient enantioselective construction of 3,4-dihydroisocoumarins. Chem. Eur. J., 2017, 23, 519–523. (Highlighted as Inside Front Cover)

17. Jindian Duan, Yuyu Cheng, Rou Li, Pengfei Li.* Synthesis of spiro[indane- 1,3-dione-1-pyrrolines] via copper-catalyzed heteroannulation of ketoxime acetates with 2-arylideneindane-1,3-diones. Org. Chem. Front., 2016, 3, 1614–1618. (Highlighted as Inside Front Cover)

16. Lu Yu, Yuyu Cheng, Rou Li, Yanhua Jiao,* Pengfei Li.* Tandem cyclization reaction between optically active γ-nitro ketone and chalcone towards the synthesis of chiral cyclohexane skeletons bearing five stereocenters. Chin. J. Org. Chem., 2016, 36, 1572–1579. (Highlighted as Front Cover)

15. Jindian Duan, Jing Cheng, Yuyu Cheng, Pengfei Li.* Synthesis of dinitrogen-fused spiro heterocycles via organocatalytic 1,3-dipolar cycloaddition of 2-arylidene-1,3- indandiones and azomethine imines. Asian J. Org. Chem., 2016, 5, 477–480.

14. Lu Yu, Zhen Yang, Jianzhao Peng, Pengfei Li.* Substrate-controlled synthesis of functionalized cyclohexanes with four stereocenters via organocatalytic asymmetric domino reaction between γ-nitro ketone and enone. Eur. J. Org. Chem., 2016, 535–540.

13. Jindian Duan, Jing Cheng, Bing Li, Fei Qi, Pengfei Li.* Enantioselective synthesis of spiro [1,3-indanedione-tetrahydrothiophene]s by organocatalytic sulfa-Michael/Michael domino reaction. Eur. J. Org. Chem., 2015, 6130–6134. 

12. Jindian Duan, Jing Cheng, Pengfei Li.* Enantioselective construction of spiro-1,3-indandiones with three stereocenters via organocatalytic Michael-aldol reaction of 2-arylideneindane-1,3-diones and nitro aldehydes. Org. Chem. Front., 2015, 2, 1048–1052.

11. Jindian Duan, Jing Cheng, Pengfei Li.* DBU catalyzed one-pot multicomponent reaction for the synthesis of spirocyclic tetrahydrothiophene derivatives. Current Organocatalysis, 2016, 3, 216–220.

10. Fang Fang, Genghong Hua, Feng Shi,* Pengfei Li.* Organocatalytic enantioselective Friedel-Crafts reaction: an efficient access to chiral isoindolo-β-carboline derivatives. Org. Biomol. Chem., 2015, 13, 4395–4398. (Highlighted as Inside Front Cover)

9. Hongqi Tao, Jindian Duan, Qijie He, Jun Wang,* Pengfei Li.* Organocatalytic efficient synthesis of 3-substituted-3-hydroxy-indolin-2-one derivatives from isatins and 4-phenylbut-3-yn-2-one. Scientia Sinica Chimica, 2015, 45(4), 391–395.

8. Lu Yu, Qingjing Yang, Pengfei Li.* Phase-transfer-catalyst-mediated domino reaction of γ-nitro ketones with chalcones: approach to functionalized six-membered-ring carbocycles. Eur. J. Org. Chem., 2014, 7499–7504.

7. Lu Yu, Pengfei Li.* New simple primary amine-thiourea organocatalysts and their application in asymmetric conjugate addition. Tetrahedron Lett., 2014, 55, 3697–3700.

6. Hongqi Tao, Jindian Duan, Pengfei Li.* Inorganic-base-catalysed synthesis of α, β- unsaturated ketones and 3,5-disubstituted cyclohex-2-en-1-ones. Asian J. Org. Chem., 2014, 3, 644–648.

5. Xin Yang, Jun Wang*, Pengfei Li.* Recent progress on asymmetric organocatalytic construction of chiral cyclohexenone skeletons. Org. Biomol. Chem., 2014, 12, 2499–2513. (Highlighted as Front Cover)

4. Pengfei Li,* Fang Fang, Ji Chen, Jun Wang.* Organocatalytic asymmetric aza-Michael addition of pyrazole to chalcone. Tetrahedron: Asymmetry, 2014, 25, 98–101.

3. Jindian Duan, Pengfei Li.* Asymmetric organocatalysis mediated by primary amines derived from cinchona alkaloids: recent advances. Catal. Sci. Technol., 2014, 4, 311–320.

2. Yinuo Wu, Fuk Yee Kwong, Pengfei Li,* Albert S C Chan.* An efficient oxidative cross-coupling reaction between C-H and N-H bonds; a transition-Metal-Free protocol at room temperature. Synlett, 2013, 24, 2009–2013.

1. Jun Wang, Pengfei Li,* Pui Ying Choy, Albert S C Chan,* Fuk Yee Kwong.* Recent advances and applications in organocatalytic asymmetric aza-Michael addition. ChemCatChem, 2012, 4, 917–925. (Invited, Highlighted as Back Cover)



指導本科生發表文章:

10. Pengfei Zhang, Xing Guo, Chang Liu, Wenjun Li,* Pengfei Li.* Org. Lett., 2019, 21, 152-155. (Highlighted by ChemBeanGo) 

9. Chenxiao Qian,? Pangmiaomiao Zhang,? Wenjun Li,* Pengfei Li.*  (?co-first author). Asian J. Org. Chem., 2019, 8, 242-245. (Highlighted by ChemBeanGo) 

8. Fei Qi, Fang Fang, Pengfei Li*. Current Organocatalysis, 2018, 5, 145–149.

7. Yuzhe Han, Yingzu Zhu, Pangmiaomiao Zhang, Wenjun Li,* Pengfei Li*. Chemistryselect, 2017, 2, 11380–11383. 

6. Yuyu Cheng, Pengfei Zhang, Yanwen Jia, Zhiqiang Fang, Pengfei Li* .Org. Biomol. Chem., 2017, 15, 7505–7508. Front Cover 

5. Lu Yu, Yuyu Cheng, Fei Qi, Rou Li, Pengfei Li*. Org. Chem. Front., 2017, 4, 1336–1340. 

4. Fei Qi, Rou Li, Fang Fang, Pengfei Li*. Current Green Chemistry, 2016, 3, 235–241. 

3. Lu Yu, Zhen Yang, Jianzhao Peng, Pengfei Li*. Eur. J. Org. Chem., 2016, 535–540. 

2. Jindian Duan, Jing Cheng, Bing Li, Fei Qi, Pengfei Li*. Eur. J. Org. Chem., 2015, 6130–6134. 

1.  Xin Yang, Jun Wang*, Pengfei Li*. Org. Biomol. Chem., 2014, 12, 2499–2513. Front Cover




指導本科生發表文章:

10. Pengfei Zhang, Xing Guo, Chang Liu, Wenjun Li,* Pengfei Li.* Org. Lett., 2019, 21, 152-155. (Highlighted by ChemBeanGo) 

9. Chenxiao Qian,? Pangmiaomiao Zhang,? Wenjun Li,* Pengfei Li.*  (?co-first author). Asian J. Org. Chem., 2019, 8, 242-245. (Highlighted by ChemBeanGo) 

8. Fei Qi, Fang Fang, Pengfei Li*. Current Organocatalysis, 2018, 5, 145–149.

7. Yuzhe Han, Yingzu Zhu, Pangmiaomiao Zhang, Wenjun Li,* Pengfei Li*. Chemistryselect, 2017, 2, 11380–11383. 

6. Yuyu Cheng, Pengfei Zhang, Yanwen Jia, Zhiqiang Fang, Pengfei Li* .Org. Biomol. Chem., 2017, 15, 7505–7508. Front Cover 

5. Lu Yu, Yuyu Cheng, Fei Qi, Rou Li, Pengfei Li*. Org. Chem. Front., 2017, 4, 1336–1340. 

4. Fei Qi, Rou Li, Fang Fang, Pengfei Li*. Current Green Chemistry, 2016, 3, 235–241. 

3. Lu Yu, Zhen Yang, Jianzhao Peng, Pengfei Li*. Eur. J. Org. Chem., 2016, 535–540. 

2. Jindian Duan, Jing Cheng, Bing Li, Fei Qi, Pengfei Li*. Eur. J. Org. Chem., 2015, 6130–6134. 

1.  Xin Yang, Jun Wang*, Pengfei Li*. Org. Biomol. Chem., 2014, 12, 2499–2513. Front Cover


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